Dissecting the relationship between childhood abuse, personality traits and genetic markers in eating disorders using a discordant sister-pair design
نویسندگان
چکیده
Method Participants were 147 discordant sister pairs (total of 297 participants) for EDs. The semi-structured EATATE interview [designed to assess ED symptomatology and obsessive-compulsive personality traits (OCPD)], the Temperament and Character Inventory (TCI-R) and the Oxford Risk Factor Interview (ORFI) were used. DNA was also collected and three candidate genes (5-HT2A, BDNF and 5-HTTLPR) were genotyped.
منابع مشابه
Individual-specific risk factors for anorexia nervosa: a pilot study using a discordant sister-pair design.
BACKGROUND The aim of this pilot study was to examine which unique factors (genetic and environmental) increase the risk for developing anorexia nervosa by using a case-control design of discordant sister pairs. METHODS Forty-five sister-pairs, one of whom had anorexia nervosa and the other did not, were recruited. Both sisters completed the Oxford Risk Factor Interview for Eating Disorders a...
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